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Structure paper

TitleCell Cycle Regulation has Shaped Budding Yeast Replication Origin Structure and Function
Journal, issue, pagesTo Be Published
Publish dateJan 23, 2025 (structure data deposition date)
AuthorsMiller, T.C.R. / Lim, C.T. / Diffley, J.F.X. / Costa, A.
External linksSearch PubMed
MethodsEM (single particle)
Resolution4.4 Å
Structure data

PDB-9i3i:
Cryo-EM structure of the MCM-ORC (MO) complex featuring an ORC2 regulatory domain involved in cell cycle regulation of MCM-DH loading for DNA replication.
Method: ELECTRON MICROSCOPY / Resolution: 4.4 Å

Chemicals

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-ZN:
Unknown entry

Source
  • saccharomyces cerevisiae s288c (yeast)
KeywordsREPLICATION / DNA Replication / Origin licensing / MCM2-7 helicase / Origin Recognition Complex / CDK / cell cycle

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