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TitlecryoEM structure of mTORC1 with the cancer-associated 1455-EWED-1458 duplication variant, overall refinement
Journal, issue, pagesTo Be Published
Publish dateDec 6, 2023 (structure data deposition date)
AuthorsAnandapadamanaban M / Hay I / Perisic O / Williams R
External linksSearch PubMed
MethodsEM (single particle)
Resolution4.0 Å
Structure data

19052

8rch

EMDB-19052, PDB-8rch:
CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, overall refinement
Method: EM (single particle) / Resolution: 4.0 Å

Chemicals

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Target of Rapamycin / mTOR / Cancer-associated mutants

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