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Structure paper

TitleInhibition of protein-only RNase P with Gambogic acid and Juglone
Journal, issue, pagesTo Be Published
Publish dateDec 12, 2017 (structure data deposition date)
AuthorsWu, N. / Karasik, A. / Muehlbauer, L. / Koutmos, M. / Fierke, C.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.79 - 2.2 Å
Structure data

PDB-6bv5:
Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana after 45-minute soak with juglone
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

PDB-6bv6:
Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana after 3-hour soak with juglone
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6bv8:
Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana complexed with Mn after 3-hour soak with juglone
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6bv9:
Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana after overnight soak with juglone
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-JUG:
5-hydroxynaphthalene-1,4-dione

ChemComp-MN:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • arabidopsis thaliana (thale cress)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / metallonuclease / PRORP / ribonuclease / PIN / tRNA processing / RNAse P / NYN domain / PPR domain / chloroplasts / mitochondria / HYDROLASE-HYDROLASE INHIBITOR complex

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