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TitleHuman anti-ACE2 monoclonal antibodies as pan-sarbecovirus prophylactic agents
Journal, issue, pagesBiorxiv, Year 2022
Publish dateAug 24, 2022 (structure data deposition date)
AuthorsZhang F / Jenkins J / de Carvalho RV / Nakandakari-Higa S / Chen T / Abernathy ME / Nyakatura E / Andrew D / Lebedeva I / Lorenz IC ...Zhang F / Jenkins J / de Carvalho RV / Nakandakari-Higa S / Chen T / Abernathy ME / Nyakatura E / Andrew D / Lebedeva I / Lorenz IC / Hoffmann HH / Rice CM / Victora GD / Barnes CO / Haziioannou T / Bieniasz PD
External linksBiorxiv / Search PubMed
MethodsEM (single particle)
Resolution3.3 Å
Structure data

27939

8e7m

EMDB-27939, PDB-8e7m:
Structure of the human ACE2 receptor in complex with antibody Fab fragment, 05B04
Method: EM (single particle) / Resolution: 3.3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsANTIVIRAL PROTEIN / ACE2 / antibody / SARS-CoV-2 / inhibition

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