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Structure paper

TitleStructural and biochemical characterization of the ALX4 dimer reveals novel insights into how disease alleles impact ALX4 function
Journal, issue, pagesTo Be Published
Publish dateAug 21, 2024 (structure data deposition date)
AuthorsYuan, Z. / Kovall, R.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.389 - 2.39 Å
Structure data

PDB-9d9r:
X-ray structure of ALX4 homeodomain dimer bound to DNA
Method: X-RAY DIFFRACTION / Resolution: 2.389 Å

PDB-9d9v:
X-Ray structure of ALX4 homeodomain
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/DNA / ALX4 / paired-like homeodomain / transcription factor / TRANSCRIPTION / TRANSCRIPTION-DNA complex

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