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Structure paper

TitleSilent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions
Journal, issue, pagesTo Be Published
Publish dateJan 8, 2021 (structure data deposition date)
AuthorsFields, J.K. / Sundberg, E.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.13 - 2.6 Å
Structure data

PDB-7lbl:
Structure of Human IgG1 Fc
Method: X-RAY DIFFRACTION / Resolution: 2.13 Å

PDB-7lf5:
Structure of Hyperglycosylated Human IgG1 Fc (Fc267)
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-7lf9:
Structure of Hyperglycosylated Human IgG1 Fc (Fc329)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-7lfn:
Structure of Hyperglycosylated Human IgG1 Fc (Fc267_329)
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-FUC:
alpha-L-fucopyranose

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Effector / IgG / Antibody / Fc

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