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TitleCryo-EM structure of human lanosterol 14alpha-demethylase (CYP51) in complex with FLZ
Journal, issue, pagesTo Be Published
Publish dateMar 19, 2024 (structure data deposition date)
AuthorsZhou LC
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.52 Å
Structure data

39501

8yqo

EMDB-39501, PDB-8yqo:
Cryo-EM structure of human lanosterol 14alpha-demethylase (CYP51) in complex with FLZ
Method: EM (single particle) / Resolution: 3.52 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

PDB-1d61:
THE STRUCTURE OF THE B-DNA DECAMER C-C-A-A-C-I-T-T-G-G: MONOCLINIC FORM

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / CYP51A1;FLZ;cryo-EM;Parkinson's disease;Alzheimer's disease

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