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TitleCrystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004
Journal, issue, pagesTo Be Published
Publish dateJul 25, 2022 (structure data deposition date)
AuthorsHuang, Y. / Wei, A. / Dong, R. / Xu, H. / Zhang, C. / Chen, Z. / Li, J. / Wu, X. / Zhang, Y. / Xu, Y.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.62 Å
Structure data

PDB-7yl2:
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

Chemicals

ChemComp-JCO:
N-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamide

ChemComp-GOL:
GLYCEROL

ChemComp-NO3:
NITRATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsANTITUMOR PROTEIN / BRD4(1) / Bromodomain / Inhibitor

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