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-Structure paper
Title | Fragment Screening Platform and Discovery of Novel Fragment Binders of the VHR Phosphatase, a Drug Target for Sepsis and Septic Shock |
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Journal, issue, pages | To Be Published |
Publish date | Jul 25, 2023 (structure data deposition date) |
Authors | Wu, J. / Baranowski, M.R. / Aleshin, A.E. / Lambert, L.J. / Isiorho, E.A. / Lemberikman, A.M. / Keedy, D.A. / Cosford, N.D.P. / Tautz, L. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.65 - 1.924 Å |
Structure data | PDB-8tk5: PDB-8tk6: PDB-9dj9: |
Chemicals | ChemComp-EPE: ChemComp-PG4: ChemComp-PE8: ChemComp-PEG: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / PROTEIN DUAL-SPECIFICITY PHOSPHATASE / VHR / Phosphatase |