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TitleCrystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with F9 ligand and the product L-Tryptophan in the beta-site.
Journal, issue, pagesTo Be Published
Publish dateJul 9, 2015 (structure data deposition date)
AuthorsHilario, E. / Caulkins, B.G. / Young, R.P. / Dunn, M.F. / Mueller, L.J. / Fan, L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.18 Å
Structure data

PDB-5cgq:
Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with F9 ligand in the alpha-site and the product L-Tryptophan in the beta-site.
Method: X-RAY DIFFRACTION / Resolution: 1.18 Å

Chemicals

ChemComp-F9F:
2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE

ChemComp-CS:
Unknown entry

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-TRP:
TRYPTOPHAN

ChemComp-BCN:
BICINE / pH buffer*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • salmonella enterica subsp. enterica serovar typhimurium (bacteria)
KeywordsLYASE/LYASE INHIBITOR / Lyase / carbon-oxygen lyase / tryptophan biosynthesis / Salmonella typhimurium / F6F / inhibitor / allosteric enzyme / aromatic amino acid biosynthesis / pyridoxal phosphate / TRANSFERASE / LYASE-LYASE INHIBITOR complex

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