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TitleCrystal structure of CREBBP bromodomain in complex with (R,E)-6-(5-(7-methoxy-3,4-dihydroquinolin-1(2H)-yl)pent-1-en-1-yl)-4-methyl-8-(morpholine-4-carbonyl)-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one
Journal, issue, pagesTo Be Published
Publish dateAug 7, 2024 (structure data deposition date)
AuthorsAmann, M. / Boyd, A. / Einsle, O. / Guenther, S. / Monoglu, M. / Conway, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.29 Å
Structure data

PDB-9get:
Crystal structure of CREBBP bromodomain in complex with (R,E)-6-(5-(7-methoxy-3,4-dihydroquinolin-1(2H)-yl)pent-1-en-1-yl)-4-methyl-8-(morpholine-4-carbonyl)-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one
Method: X-RAY DIFFRACTION / Resolution: 1.29 Å

Chemicals

PDB-1ikm:
NMR study of monomeric human interleukin-8 (30 structures)

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / bromodomain / CREBBP / protein-inhibitor complex

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