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Structure paper

TitleComprehensive structural overview of the HCV IRES-mediated translation initiation pathway
Journal, issue, pagesTo Be Published
Publish dateNov 25, 2021 (structure data deposition date)
AuthorsBrown ZP / Abaeva IS / De S / Hellen CUT / Pestova TV / Frank J
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.5 - 4.8 Å
Structure data

25533

7sym

EMDB-25533, PDB-7sym:
Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII)
Method: EM (single particle) / Resolution: 4.8 Å

EMDB-25590: Consensus map of 40S ribosome with head motion from wt IRES eIF2-containing sample
Method: EM (single particle) / Resolution: 3.5 Å

EMDB-25591: Consensus map of 40S ribosome with head motion from wt IRES eIF5B-containing sample
Method: EM (single particle) / Resolution: 4.5 Å

EMDB-25592: Consensus map of 40S ribosome showing IRES binding
Method: EM (single particle) / Resolution: 3.6 Å

EMDB-25593: Consensus map of 40S ribosome with head motion from wt IRES eIF5B-, and eIF2-containing sample
Method: EM (single particle) / Resolution: 3.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • oryctolagus cuniculus (rabbit)
  • hepatitis c virus (isolate 1)
KeywordsRIBOSOME / HCV / IRES / 40S

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