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| Title | Structural insights into cohesin cleavage by human separase |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Dec 6, 2024 (structure data deposition date) |
Authors | Yu J / Schmidt S / Botto M / Ghent CM / Morgan DO / Boland A |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.77 - 3.45 Å |
| Structure data | EMDB-52288, PDB-9hm7: EMDB-52290, PDB-9hma: ![]() EMDB-52291: Focus-refined map (mask 1) of human separase bound to SCC1 (310-550 aa) and SA2 ![]() EMDB-52294: Focus-refined map (mask 2) of human separase bound to SCC1 (310-550 aa) and SA2 ![]() EMDB-52295: Consensus map of human separase bound to SCC1 (310-550 aa) and SA2 EMDB-52297, PDB-9hms: EMDB-52298, PDB-9hmv: ![]() EMDB-52300: Focus-refined map of human separase bound to SCC1 (310-550 aa) with a mask on TPR-like domain and SPD ![]() EMDB-52301: Focus-refined map of human separase bound to SCC1 (310-550 aa) with a mask on HEAT-repeat domain ![]() EMDB-52302: Consensus map of human separase bound to SCC1 (310-550 aa) EMDB-52303, PDB-9hn0: EMDB-52306, PDB-9hn4: EMDB-52307, PDB-9hn5: |
| Chemicals | ![]() ChemComp-ZN: |
| Source |
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Keywords | CELL CYCLE / Separase / SCC1 / RAD21 / protease / chromosome segregation / Auto-cleavage / SA1/2 / cohesin |
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homo sapiens (human)
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