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Structure paper

TitleIdentification of a single tryptophan residue as critical for binding activity in a humanized monoclonal antibody against respiratory syncytial virus
Journal, issue, pagesTo be Published
Publish dateAug 2, 2006 (structure data deposition date)
AuthorsWei, Z. / Feng, J. / Lin, H.-Y. / Mullapudi, S. / Bishop, E. / Tous, G. / Casas-Finet, J. / Hakki, F. / Strouse, R. / Schenerman, M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-2hwz:
Fab fragment of Humanized anti-viral antibody MEDI-493 (Synagis TM)
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Immunoglobulin / Fab fragment

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