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Structure paper

TitleStructural basis for kainate receptor activation by a partial agonist
Journal, issue, pagesTo Be Published
Publish dateMar 1, 2023 (structure data deposition date)
AuthorsBogdanovic N / Tajima N
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.8 - 4.1 Å
Structure data

29926

8gc2

EMDB-29926, PDB-8gc2:
Domoate-bound GluK2 kainate receptor in partially-open conformation 1
Method: EM (single particle) / Resolution: 4.1 Å

29927

8gc3

EMDB-29927, PDB-8gc3:
Domote-bound GluK2 kainate receptors in partially-open conformation 2
Method: EM (single particle) / Resolution: 3.8 Å

29928

8gc4

EMDB-29928, PDB-8gc4:
Domoate-bound GluK2 kainate receptor in partially-open conformation 3
Method: EM (single particle) / Resolution: 3.93 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-DOQ:
(2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID

Source
  • rattus norvegicus (Norway rat)
KeywordsMEMBRANE PROTEIN / ion channel / glutamate kainate receptor 2 / homotetramer / partial agonist / gating mechanism

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