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Structure paper

TitleNew enzyme lineages by subdomain shuffling.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 95, Page 9813-9818, Year 1998
Publish dateApr 22, 1998 (structure data deposition date)
AuthorsHopfner, K.P. / Kopetzki, E. / Kresse, G.B. / Bode, W. / Huber, R. / Engh, R.A.
External linksProc. Natl. Acad. Sci. USA / PubMed:9707558
MethodsX-ray diffraction
Resolution2.15 Å
Structure data

PDB-1fxy:
COAGULATION FACTOR XA-TRYPSIN CHIMERA INHIBITED WITH D-PHE-PRO-ARG-CHLOROMETHYLKETONE
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-0G6:
D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
Keywordshydrolase/hydrolase inhibitor / CHIMERA / PROTEASE / CHLOROMETHYLKETONE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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