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Structure paper

TitleStructural basis for chemical inhibition of human blood coagulation factor Xa.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 95, Page 6630-6635, Year 1998
Publish dateMar 19, 1998 (structure data deposition date)
AuthorsKamata, K. / Kawamoto, H. / Honma, T. / Iwama, T. / Kim, S.H.
External linksProc. Natl. Acad. Sci. USA / PubMed:9618463
MethodsX-ray diffraction
Resolution2.3 - 2.4 Å
Structure data

PDB-1xka:
FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'-AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1xkb:
FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'-AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-4PP:
(2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsBLOOD COAGULATION FACTOR / SERINE PROTEINASE / EPIDERMAL GROWTH FACTOR LIKE DOMAIN

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