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Structure paper

TitleCrystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus.
Journal, issue, pagesNat. Struct. Biol., Vol. 5, Page 357-362, Year 1998
Publish dateMar 31, 1998 (structure data deposition date)
AuthorsHennig, M. / D'Arcy, A. / Hampele, I.C. / Page, M.G. / Oefner, C. / Dale, G.E.
External linksNat. Struct. Biol. / PubMed:9586996
MethodsX-ray diffraction
Resolution1.65 - 2.2 Å
Structure data

PDB-1dhn:
1.65 ANGSTROM RESOLUTION STRUCTURE OF 7,8-DIHYDRONEOPTERIN ALDOLASE FROM STAPHYLOCOCCUS AUREUS
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-2dhn:
COMPLEX OF 7,8-DIHYDRONEOPTERIN ALDOLASE FROM STAPHYLOCOCCUS AUREUS WITH 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 2.2 A RESOLUTION
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PH2:
2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE

Source
  • staphylococcus aureus (bacteria)
KeywordsPTERIN BINDING / FOLATE BIOSYNTHESIS / ANTIBIOTIC TARGET / BETA-BARREL / PRODUCT COMPLEX / PTERINE BINDING

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