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TitleSubstrate and inhibitor binding sites in Corynebacterium glutamicum diaminopimelate dehydrogenase.
Journal, issue, pagesBiochemistry, Vol. 37, Page 3278-3285, Year 1998
Publish dateDec 23, 1997 (structure data deposition date)
AuthorsScapin, G. / Cirilli, M. / Reddy, S.G. / Gao, Y. / Vederas, J.C. / Blanchard, J.S.
External linksBiochemistry / PubMed:9521647
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-2dap:
C. GLUTAMICUM DAP DEHYDROGENASE IN COMPLEX WITH DAP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3dap:
C. GLUTAMICUM DAP DEHYDROGENASE IN COMPLEX WITH NADP+ AND THE INHIBITOR 5S-ISOXAZOLINE
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-API:
2,6-DIAMINOPIMELIC ACID

ChemComp-HOH:
WATER

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-DA3:
(2S,5',S)-2-AMINO-3-(3-CARBOXY-2-ISOXAZOLIN-5-YL)PROPANOIC ACID

Source
  • corynebacterium glutamicum (bacteria)
KeywordsOXIDOREDUCTASE / DEHYDROGENASE / D-AMINO ACID DEHYDROGENASE / LYSINE BIOSYNTHESIS / DIAMINOPIMELATE / NADP / ASYMMETRIC DIMER / INHIBITOR

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