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TitleHirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex.
Journal, issue, pagesProtein Sci., Vol. 7, Page 243-253, Year 1998
Publish dateJul 17, 1997 (structure data deposition date)
AuthorsDe Simone, G. / Lombardi, A. / Galdiero, S. / Nastri, F. / Della Morte, R. / Staiano, N. / Pedone, C. / Bolognesi, M. / Pavone, V.
External linksPubMed:9521099
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-5gds:
HIRUNORMS ARE TRUE HIRUDIN MIMETICS. THE CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN:HIRUNORM V COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / SERINE PROTEASE-INHIBITOR complex / THROMBIN / THROMBIN SYNTHETIC INHIBITORS / ANTITHROMBOTICS / HIRUNORMS / HIRUDIN-LIKE BINDING MODE / BLOOD COAGULATION / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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