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TitleThe solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.
Journal, issue, pagesJ. Mol. Biol., Vol. 277, Page 119-134, Year 1998
Publish dateJul 22, 1997 (structure data deposition date)
AuthorsGargaro, A.R. / Soteriou, A. / Frenkiel, T.A. / Bauer, C.J. / Birdsall, B. / Polshakov, V.I. / Barsukov, I.L. / Roberts, G.C. / Feeney, J.
External linksJ. Mol. Biol. / PubMed:9514736
MethodsNMR (solution)
Structure data

PDB-1ao8:
DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES
Method: SOLUTION NMR

Chemicals

ChemComp-MTX:
METHOTREXATE / chemotherapy*YM

Source
  • lactobacillus casei (bacteria)
KeywordsOXIDOREDUCTASE / INHIBITOR-ENZYME COMPLEX

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