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Structure paper

TitleA link between protein structure and enzyme catalyzed hydrogen tunneling.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 94, Page 12797-12802, Year 1997
Publish dateOct 15, 1997 (structure data deposition date)
AuthorsBahnson, B.J. / Colby, T.D. / Chin, J.K. / Goldstein, B.M. / Klinman, J.P.
External linksProc. Natl. Acad. Sci. USA / PubMed:9371755
MethodsX-ray diffraction
Resolution2 - 2.5 Å
Structure data

PDB-1axe:
CRYSTAL STRUCTURE OF THE ACTIVE-SITE MUTANT PHE93->TRP OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH NAD AND INHIBITOR TRIFLUOROETHANOL
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1axg:
CRYSTAL STRUCTURE OF THE VAL203->ALA MUTANT OF LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH COFACTOR NAD AND INHIBITOR TRIFLUOROETHANOL SOLVED TO 2.5 ANGSTROM RESOLUTION
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-ETF:
TRIFLUOROETHANOL

ChemComp-HOH:
WATER

Source
  • equus caballus (horse)
KeywordsOXIDOREDUCTASE / OXIDOREDUCTASE (NAD(A)-CHOH(D)) / ALCOHOL DEHYDROGENASE

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