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Structure paper

TitleStructures of class pi glutathione S-transferase from human placenta in complex with substrate, transition-state analogue and inhibitor.
Journal, issue, pagesStructure, Vol. 5, Page 1287-1295, Year 1997
Publish dateAug 1, 1997 (structure data deposition date)
AuthorsPrade, L. / Huber, R. / Manoharan, T.H. / Fahl, W.E. / Reuter, W.
External linksStructure / PubMed:9351803
MethodsX-ray diffraction
Resolution1.8 - 2 Å
Structure data

PDB-1aqv:
GLUTATHIONE S-TRANSFERASE IN COMPLEX WITH P-BROMOBENZYLGLUTATHIONE
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

PDB-1aqw:
GLUTATHIONE S-TRANSFERASE IN COMPLEX WITH GLUTATHIONE
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1aqx:
GLUTATHIONE S-TRANSFERASE IN COMPLEX WITH MEISENHEIMER COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-0HG:
N-[(4S)-4-ammonio-4-carboxybutanoyl]-S-(4-bromobenzyl)-L-cysteinylglycine

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-GSH:
GLUTATHIONE

ChemComp-GTD:
1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX / CLASS PI / transferase/substrate / TRANSFERASE / GLUTATHIONE S-TRANSFERASE / transferase-substrate complex / TRANSITION STATE

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