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TitleThe three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition.
Journal, issue, pagesJ. Biol. Chem., Vol. 272, Page 19931-19937, Year 1997
Publish dateMay 15, 1997 (structure data deposition date)
AuthorsStubbs, M.T. / Morenweiser, R. / Sturzebecher, J. / Bauer, M. / Bode, W. / Huber, R. / Piechottka, G.P. / Matschiner, G. / Sommerhoff, C.P. / Fritz, H. / Auerswald, E.A.
External linksJ. Biol. Chem. / PubMed:9242660
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1ldt:
COMPLEX OF LEECH-DERIVED TRYPTASE INHIBITOR WITH PORCINE TRYPSIN
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • hirudo medicinalis (medicinal leech)
  • sus scrofa (pig)
KeywordsCOMPLEX (HYDROLASE/INHIBITOR) / COMPLEX (HYDROLASE-INHIBITOR) / HYDROLASE / INHIBITOR / INFLAMMATION / TRYPTASE / COMPLEX (HYDROLASE-INHIBITOR) complex

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