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TitleThe primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 94, Page 7176-7181, Year 1997
Publish dateJun 3, 1997 (structure data deposition date)
AuthorsPratt, K.P. / Cote, H.C. / Chung, D.W. / Stenkamp, R.E. / Davie, E.W.
External linksProc. Natl. Acad. Sci. USA / PubMed:9207064
MethodsX-ray diffraction
Resolution2.01 - 2.1 Å
Structure data

PDB-2fib:
RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) COMPLEXED TO THE PEPTIDE GLY-PRO-ARG-PRO AT PH 6.0
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

PDB-3fib:
RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) BOUND TO CALCIUM AT PH 6.0: A FURTHER REFINEMENT OF PDB ENTRY 1FIB, AND DIFFERS FROM 1FIB BY THE MODELLING OF A CIS PEPTIDE BOND BETWEEN RESIDUES K338 AND C339
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCOMPLEX (BLOOD COAGULATION/PEPTIDE) / FIBRINOGEN / BLOOD COAGULATION / FIBRIN POLYMERIZATION / COMPLEX (BLOOD COAGULATION-PEPTIDE) / COMPLEX (BLOOD COAGULATION-PEPTIDE) complex / CIS PEPTIDE BONDS

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