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Structure paper

TitleThe second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa.
Journal, issue, pagesJ. Mol. Biol., Vol. 269, Page 395-407, Year 1997
Publish dateFeb 19, 1997 (structure data deposition date)
AuthorsBurgering, M.J. / Orbons, L.P. / van der Doelen, A. / Mulders, J. / Theunissen, H.J. / Grootenhuis, P.D. / Bode, W. / Huber, R. / Stubbs, M.T.
External linksJ. Mol. Biol. / PubMed:9199408
MethodsNMR (solution) / X-ray diffraction
Resolution2.6 Å
Structure data

PDB-1adz:
THE SOLUTION STRUCTURE OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR, NMR, 30 STRUCTURES
Method: SOLUTION NMR

PDB-1tfx:
COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • sus scrofa (pig)
KeywordsHYDROLASE / INHIBITOR / COAGULATION / COMPLEX (SERINE PROTEASE/INHIBITOR) / COMPLEX (SERINE PROTEASE-INHIBITOR) / BLOOD COAGULATION / COMPLEX (SERINE PROTEASE-INHIBITOR) complex

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