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TitleA new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist.
Journal, issue, pagesNature, Vol. 386, Page 194-200, Year 1997
Publish dateApr 9, 1998 (structure data deposition date)
AuthorsSchreuder, H. / Tardif, C. / Trump-Kallmeyer, S. / Soffientini, A. / Sarubbi, E. / Akeson, A. / Bowlin, T. / Yanofsky, S. / Barrett, R.W.
External linksNature / PubMed:9062194
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-1ira:
COMPLEX OF THE INTERLEUKIN-1 RECEPTOR WITH THE INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL1RA)
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCOMPLEX (CYTOKINE RECEPTOR/ANTAGONIST) / CYTOKINE RECEPTOR / RECEPTOR ANTAGONIST / IMMUNOGLOBULIN FOLD / COMPLEX (CYTOKINE RECEPTOR-ANTAGONIST) / COMPLEX (CYTOKINE RECEPTOR-ANTAGONIST) complex

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