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Structure paper

TitleRas/Rap effector specificity determined by charge reversal.
Journal, issue, pagesNat. Struct. Biol., Vol. 3, Page 723-729, Year 1996
Publish dateJun 18, 1996 (structure data deposition date)
AuthorsNassar, N. / Horn, G. / Herrmann, C. / Block, C. / Janknecht, R. / Wittinghofer, A.
External linksNat. Struct. Biol. / PubMed:8756332
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1gua:
HUMAN RAP1A, RESIDUES 1-167, DOUBLE MUTANT (E30D,K31E) COMPLEXED WITH GPPNHP AND THE RAS-BINDING-DOMAIN OF HUMAN C-RAF1, RESIDUES 51-131
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCOMPLEX (GTP-BINDING/ATP-BINDING) / ONCOGENE PROTEIN/KINASE/EFFECTOR PROTEIN GTP-BINDING-PROTEIN / COMPLEX (GTP-BINDING-ATP-BINDING) / COMPLEX (GTP-BINDING-ATP-BINDING) complex

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