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TitleDeterminants of cofactor specificity in isocitrate dehydrogenase: structure of an engineered NADP+ --> NAD+ specificity-reversal mutant.
Journal, issue, pagesBiochemistry, Vol. 35, Page 5670-5678, Year 1996
Publish dateMar 1, 1996 (structure data deposition date)
AuthorsHurley, J.H. / Chen, R. / Dean, A.M.
External linksBiochemistry / PubMed:8639526
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1iso:
ISOCITRATE DEHYDROGENASE: STRUCTURE OF AN ENGINEERED NADP+--> NAD+ SPECIFICITY-REVERSAL MUTANT
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsOXIDOREDUCTASE / NADP / PHOSPHORYLATION / GLYOXYLATE BYPASS

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