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Structure paper

TitleCrystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Journal, issue, pagesScience, Vol. 271, Page 1247-1254, Year 1996
Publish dateJan 3, 1996 (structure data deposition date)
AuthorsLewis, M. / Chang, G. / Horton, N.C. / Kercher, M.A. / Pace, H.C. / Schumacher, M.A. / Brennan, R.G. / Lu, P.
External linksPubMed:8638105
MethodsX-ray diffraction
Resolution2.7 - 4.8 Å
Structure data

PDB-1lbg:
LACTOSE OPERON REPRESSOR BOUND TO 21-BASE PAIR SYMMETRIC OPERATOR DNA, ALPHA CARBONS ONLY
Method: X-RAY DIFFRACTION / Resolution: 4.8 Å

PDB-1lbh:
INTACT LACTOSE OPERON REPRESSOR WITH GRATUITOUS INDUCER IPTG
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-1lbi:
LAC REPRESSOR
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-IPT:
1-methylethyl 1-thio-beta-D-galactopyranoside

Source
  • escherichia coli (E. coli)
KeywordsTRANSCRIPTION/DNA / TRANSCRIPTION REGULATION / DNA-BINDING / REPRESSOR / TRANSCRIPTION-DNA COMPLEX

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