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Structure paper

TitleCrystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes
Journal, issue, pagesNat. Struct. Biol., Vol. 3, Page 364-, Year 1996
Publish dateJun 3, 2006 (structure data deposition date)
AuthorsNolte, R.T. / Eck, M.J. / Schlessinger, J. / Shoelson, S.E. / Harrison, S.C.
External linksNat. Struct. Biol. / PubMed:8599763
MethodsX-ray diffraction
Resolution1.89 - 2.4 Å
Structure data

PDB-2iug:
Crystal structure of the PI3-kinase p85 N-terminal SH2 domain
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

PDB-2iuh:
Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with c-Kit phosphotyrosyl peptide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2iui:
Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with PDGFR phosphotyrosyl peptide
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / POLYMORPHISM / UBL CONJUGATION / PHOSPHORYLATION / P85 / SH2 / PI3K / SH2 DOMAIN / SH3 DOMAIN / PI3-KINASE / DISEASE MUTATION

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