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TitleCrystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(CGTACG) and d(CGATCG): implications in drug-DNA crosslink.
Journal, issue, pagesJ. Biomol. Struct. Dyn., Vol. 13, Page 103-117, Year 1995
Publish dateJun 22, 1995 (structure data deposition date)
AuthorsGao, Y.G. / Wang, A.H.
External linksPubMed:8527023
MethodsX-ray diffraction
Resolution1.7 - 1.8 Å
Structure data

PDB-215d:
CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-234d:
CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-235d:
CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-236d:
CRYSTAL STRUCTURE OF FOUR MORPHOLINO-DOXORUBICIN ANTICANCER DRUGS COMPLEXED WITH D(CGTACG) AND D(CGATCG): IMPLICATIONS IN DRUG-DNA CROSSLINK
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-DMM:
3'-DESAMINO-3'-(2-METHOXY-4-MORPHOLINYL)-DOXORUBICIN

ChemComp-HOH:
WATER

ChemComp-CMD:
3'-DESAMINO-3'-(3-CYANO-4-MORPHOLINYL)-DOXORUBICIN

KeywordsDNA / RIGHT HANDED DNA / DOUBLE HELIX / COMPLEXED WITH DRUG

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