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Structure paper

TitleWater-mediated substrate/product discrimination: the product complex of thymidylate synthase at 1.83 A.
Journal, issue, pagesBiochemistry, Vol. 33, Page 1502-1511, Year 1994
Publish dateMay 7, 1993 (structure data deposition date)
AuthorsFauman, E.B. / Rutenber, E.E. / Maley, G.F. / Maley, F. / Stroud, R.M.
External linksBiochemistry / PubMed:8312270
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-1tys:
WATER-MEDIATED SUBSTRATE(SLASH)PRODUCT DISCRIMINATION: THE PRODUCT COMPLEX OF THYMIDYLATE SYNTHASE AT 1.83 ANGSTROMS
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-TMP:
THYMIDINE-5'-PHOSPHATE

ChemComp-DHF:
DIHYDROFOLIC ACID

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / METHYLTRANSFERASE

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