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TitleCrystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin.
Journal, issue, pagesNature, Vol. 377, Page 649-652, Year 1995
Publish dateApr 23, 1997 (structure data deposition date)
AuthorsTakahara, P.M. / Rosenzweig, A.C. / Frederick, C.A. / Lippard, S.J.
External linksNature / PubMed:7566180
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-1aio:
CRYSTAL STRUCTURE OF A DOUBLE-STRANDED DNA CONTAINING THE MAJOR ADDUCT OF THE ANTICANCER DRUG CISPLATIN
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-CPT:
Cisplatin / medication, chemotherapy*YM

ChemComp-HOH:
WATER

KeywordsDNA / RIGHT HANDED DNA / DOUBLE HELIX / COMPLEXED WITH DRUG / MODIFIED

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