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Structure paper

TitleThe structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase.
Journal, issue, pagesNat. Struct. Biol., Vol. 2, Page 637-643, Year 1995
Publish dateApr 11, 1995 (structure data deposition date)
AuthorsLoll, P.J. / Picot, D. / Garavito, R.M.
External linksNat. Struct. Biol. / PubMed:7552725
MethodsX-ray diffraction
Resolution3.4 Å
Structure data

PDB-1pth:
The Structural Basis of Aspirin Activity Inferred from the Crystal Structure of Inactivated Prostaglandin H2 Synthase
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-BOG:
octyl beta-D-glucopyranoside / detergent*YM

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-SAL:
2-HYDROXYBENZOIC ACID

ChemComp-HOH:
WATER

Source
  • ovis aries (sheep)
KeywordsOXIDOREDUCTASE / DIOXYGENASE / PEROXIDASE

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