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TitleDiscovery, Structural Characterization, and Preclinical Evaluation of Monoclonal Antibodies against Xylazine Poisoning.
Journal, issue, pagesAcs Pharmacol Transl Sci, Vol. 9, Page 1881-1892, Year 2026
Publish dateJan 10, 2026 (structure data deposition date)
AuthorsKang, J. / Xu, R. / Lee, S. / Luengas, D. / Kim, C.M. / Marecki, C. / Gallant, J. / Moeller, N. / Shi, K. / Jahan, R. ...Kang, J. / Xu, R. / Lee, S. / Luengas, D. / Kim, C.M. / Marecki, C. / Gallant, J. / Moeller, N. / Shi, K. / Jahan, R. / Hicks, D. / Runyon, S. / Aihara, H. / Pravetoni, M.
External linksAcs Pharmacol Transl Sci / PubMed:42453353
MethodsX-ray diffraction
Resolution1.99 Å
Structure data

PDB-10bt:
X-ray Crystal Structure of A High-Affinity Monoclonal Antibody Sequesters Xylazine
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

Chemicals

PDB-1c4r:
THE STRUCTURE OF THE LIGAND-BINDING DOMAIN OF NEUREXIN 1BETA: REGULATION OF LNS DOMAIN FUNCTION BY ALTERNATIVE SPLICING

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / monoclonal antibody

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