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-Structure paper
| Title | DNA-Encoded Library (DEL) Selection Identifies a Distinct DDB1 Ligand Binding Site. |
|---|---|
| Journal, issue, pages | Acs Med. Chem. Lett., Vol. 17, Page 757-767, Year 2026 |
| Publish date | Jan 5, 2026 (structure data deposition date) |
 Authors | Reddy Guduru, S.K. / Caldwell, J.P. / Digianantonio, K.M. / Prophet, S.M. / Yang, S. / Gareiss, P. / Jones, C. / Harbin, A. / Driscoll, B. / Karim, M.F. ...Reddy Guduru, S.K. / Caldwell, J.P. / Digianantonio, K.M. / Prophet, S.M. / Yang, S. / Gareiss, P. / Jones, C. / Harbin, A. / Driscoll, B. / Karim, M.F. / Scott, A. / Patel, A. / Chapman, A.E. / Crandall, M. / Miklossy, G. / Barczak, N.T. / Stroppa, A.P. / Corradi, J.P. / Clark, J.J. / Chung, M.K. / Reinhardt, N.R. / Butcher, W.E. / Wilson, R. / Stiff, C. / Fathizadeh, A. / Yuan, L. / Wang, G. / Dong, H. / Beno, B.R. / Zimmermann, K. / Langley, D.R. / Cacace, A.M. / Bekes, M. |
 External links | Acs Med. Chem. Lett. / PubMed:41982729 |
| Methods | X-ray diffraction |
| Resolution | 2.07 - 2.195 Å |
| Structure data |  PDB-9zxm:  PDB-9zxn: |
| Chemicals |  PDB-1c4e:  ChemComp-GOL:  ChemComp-HOH:  PDB-1c4f: |
| Source |
|
 Keywords | LIGASE / E3 Ligase / DNA-encoded library |
homo sapiens (human)