Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Structure-Based Design of 4-(1-Methyl-1 H -indol-3-yl)pyrimidin-2-amine Derivatives as the First Covalent FGFR3 Selective Inhibitors.
Journal, issue, pages	J. Med. Chem., Vol. 69, Page 5199-5218, Year 2026
Publish date	Jun 25, 2025 (structure data deposition date)
Authors	Zhu, W. / Chen, X. / Li, X. / Lin, J. / Lin, X. / Liu, X. / Deng, W. / Song, X. / Tu, Z. / Patterson, A.V. ...Zhu, W. / Chen, X. / Li, X. / Lin, J. / Lin, X. / Liu, X. / Deng, W. / Song, X. / Tu, Z. / Patterson, A.V. / Smaill, J.B. / Chen, Y. / Lu, X.
External links	J. Med. Chem. / PubMed:41648938
Methods	X-ray diffraction
Resolution	1.81 - 2.65 Å
Structure data	PDB-9vlj: Crystal structure of FGFR1 in complex with covalent inhibitor 10a Method: X-RAY DIFFRACTION / Resolution: 1.81 Å PDB-9vlm: The X-RAY co-crystal structure of human FGFR2 and covalent inhibitor 10a Method: X-RAY DIFFRACTION / Resolution: 2.26 Å PDB-9vm9: Crystal structure of FGFR3 in complex with 10s Method: X-RAY DIFFRACTION / Resolution: 2.65 Å PDB-9vmb: The X-RAY co-crystal structure of human FGFR3 and Compound 10t Method: X-RAY DIFFRACTION / Resolution: 1.97 Å
Chemicals	PDB-1esp: NEUTRAL PROTEASE MUTANT E144S ChemComp-SO4: SULFATE ION ChemComp-HOH: WATER ChemComp-GOL: GLYCEROL PDB-1esw: X-RAY STRUCTURE OF ACARBOSE BOUND TO AMYLOMALTASE FROM THERMUS AQUATICUS. IMPLICATIONS FOR THE SYNTHESIS OF LARGE CYCLIC GLUCANS ChemComp-MG: Unknown entry PDB-1esx: 1H, 15N AND 13C STRUCTURE OF THE HIV-1 REGULATORY PROTEIN VPR : COMPARISON WITH THE N-AND C-TERMINAL DOMAIN STRUCTURE, (1-51)VPR AND (52-96)VPR
Source	homo sapiens (human)
Keywords	TRANSFERASE / FGFR1 / FGFR2 / FGFR3