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TitleDivergent viral phosphodiesterases for immune signaling evasion.
Journal, issue, pagesCell Host Microbe, Vol. 33, Page 2043-2051.e6, Year 2025
Publish dateAug 15, 2025 (structure data deposition date)
AuthorsDoherty, E.E. / Nomburg, J. / Adler, B.A. / Lopez, S. / Hsieh, K. / Price, N. / Blount, N. / Doudna, J.A.
External linksCell Host Microbe / PubMed:41297541
MethodsX-ray diffraction
Resolution2 - 2.03 Å
Structure data

PDB-9q2g:
Phosphodiesterase from Burkholderia phage BCSR5 in the closed lid conformation
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-9q2y:
Phosphodiesterase from Burkholderia phage BCSR5 in the open lid conformation
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-FLC:
CITRATE ANION

ChemComp-HOH:
WATER

ChemComp-CAC:
CACODYLATE ION

Source
  • burkholderia phage bcsr5 (virus)
KeywordsVIRAL PROTEIN / Phosphodiesterase

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