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| Title | Engineering ultrapotent trivalent anticoagulants through hybridisation of salivary peptides from multiple haematophagous organisms. |
|---|---|
| Journal, issue, pages | Chem Sci, Vol. 16, Page 18660-18672, Year 2025 |
| Publish date | Jan 26, 2024 (structure data deposition date) |
Authors | Maxwell, J.W.C. / Ripoll-Rozada, J. / Mackay, A.S. / Alwis, I. / Ford, D.J. / Trought, C.B.J. / Santos, J.A. / Smythe, R.E. / Liu, J.S.T. / Zuccolotto, Z. ...Maxwell, J.W.C. / Ripoll-Rozada, J. / Mackay, A.S. / Alwis, I. / Ford, D.J. / Trought, C.B.J. / Santos, J.A. / Smythe, R.E. / Liu, J.S.T. / Zuccolotto, Z. / Schoenwaelder, S.M. / Jackson, S.P. / Pereira, P.J.B. / Payne, R.J. |
External links | Chem Sci / PubMed:40959396 |
| Methods | X-ray diffraction |
| Resolution | 2.51 Å |
| Structure data | ![]() PDB-8rtn: |
| Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-NA: ![]() ChemComp-HOH: |
| Source |
|
Keywords | BLOOD CLOTTING / inhibitor / tyrosine-o-sulfate |
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homo sapiens (human)
glossina morsitans morsitans (fry)
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