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Structure paper

TitleStructural analysis of ASCH domain-containing proteins and their implications for nucleotide processing.
Journal, issue, pagesStructure, Vol. 33, Page 2095-2108.e5, Year 2025
Publish dateDec 9, 2024 (structure data deposition date)
AuthorsMeng, C. / Shi, X. / Guo, W. / Jian, X. / Zhao, J. / Wen, Y. / Wang, R. / Li, Y. / Xu, S. / Chen, H. ...Meng, C. / Shi, X. / Guo, W. / Jian, X. / Zhao, J. / Wen, Y. / Wang, R. / Li, Y. / Xu, S. / Chen, H. / Zhang, J. / Chen, M. / Wu, B.
External linksStructure / PubMed:40939588
MethodsX-ray diffraction
Resolution1.02 - 2.15 Å
Structure data

PDB-9kyf:
Crystal structure of E.coli ac4C amidohydrolase YqfB
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-9kyg:
Crystal structure of E.coli ac4C amidohydrolase YqfB in complex with cytidine
Method: X-RAY DIFFRACTION / Resolution: 1.47 Å

PDB-9kyh:
Crystal structure of E.coli ac4C amidohydrolase YqfB in complex with ac4C
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

PDB-9kyi:
Crystal structure of mouse Endothelial-overexpressed lipopolysaccharide-associated factor 1 (EOLA1)
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-9kyj:
Crystal structure of mouse Endothelial-overexpressed lipopolysaccharide-associated factor 1 (EOLA1), Selenomethionine derivative
Method: X-RAY DIFFRACTION / Resolution: 1.57 Å

PDB-9kyk:
Crystal structure of human TRIP4
Method: X-RAY DIFFRACTION / Resolution: 1.02 Å

PDB-9kyl:
Crystal structure of human TRIP4 in complex with 11bp dsDNA
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CTN:
4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE

ChemComp-MG:
Unknown entry

PDB-1eht:
THEOPHYLLINE-BINDING RNA IN COMPLEX WITH THEOPHYLLINE, NMR, 10 STRUCTURES

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

Source
  • escherichia coli bl21(de3) (bacteria)
  • mus musculus (house mouse)
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE / N4-acetylcytidine / RNA modification / amidohydrolase / cytidine / complex / IMMUNE SYSTEM / ASCH domain / DNA BINDING PROTEIN / DNA BINDING PROTEIN/DNA / dsDNA / DNA BINDING PROTEIN-DNA complex

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