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Structure paper

TitleIdentifying 14-3-3 interactome binding sites with deep learning.
Journal, issue, pagesDigit Discov, Vol. 4, Page 2602-2614, Year 2025
Publish dateMar 25, 2025 (structure data deposition date)
Authorsvan Weesep, L. / Ozcelik, R. / Pennings, M. / Criscuolo, E. / Ottmann, C. / Brunsveld, L. / Grisoni, F.
External linksDigit Discov / PubMed:40837623
MethodsX-ray diffraction
Resolution1.3 - 1.8 Å
Structure data

PDB-9qng:
FOXO3 pS413 phosphopeptide binding to 14-3-3sigma
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-9qnh:
Myc pS294 phosphopeptide binding to 14-3-3sigma
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-9qni:
NOTCH4 phosphopeptide binding to 14-3-3sigma
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-9qnj:
Tau pS198 phosphopeptide binding to 14-3-3sigma
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-9qnk:
Tau pT245 phosphopeptide binding to 14-3-3sigma
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-9qnl:
BAD pS118 phosphopeptide binding to 14-3-3sigma
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsPEPTIDE BINDING PROTEIN / 14-3-3 protein-protein interactions

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