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TitleIgE clonality and aggregation of insulin affect IgE-mediated activation of sensitized basophils.
Journal, issue, pagesJ Allergy Clin Immunol Glob, Vol. 4, Page 100502-100502, Year 2025
Publish dateApr 3, 2023 (structure data deposition date)
AuthorsChristoffersen, S. / Baumann, K. / Millner, A.H. / Toft-Hansen, H. / Johansson, E. / Thorlaksen, C. / Skov, P.S.
External linksJ Allergy Clin Immunol Glob / PubMed:40583959
MethodsX-ray diffraction
Resolution2.3 - 3.403 Å
Structure data

PDB-8oni:
Human insulin in complex with the analytical antibody S1 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-8onk:
Human insulin in complex with the analytical antibody S1 Fab and the analytical antibody HUI-001 Fab
Method: X-RAY DIFFRACTION / Resolution: 3.403 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsHORMONE / insulin / analytical antibody / S1 / HUI-001

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