Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Structure-Based Design of Potent and Selective MerTK Inhibitors by Modulating the Conformation of alpha C Helix.
Journal, issue, pages	J. Med. Chem., Vol. 68, Page 10877-10896, Year 2025
Publish date	Nov 29, 2024 (structure data deposition date)
Authors	Peng, Y.H. / Li, M.C. / Yen, W.C. / Yeh, T.K. / Hsueh, C.C. / Kuo, F.M. / Lai, Y.L. / Chang, L. / Lee, L.C. / Chen, P.Y. ...Peng, Y.H. / Li, M.C. / Yen, W.C. / Yeh, T.K. / Hsueh, C.C. / Kuo, F.M. / Lai, Y.L. / Chang, L. / Lee, L.C. / Chen, P.Y. / Yen, K.J. / Chang, T.Y. / Sun, H.Y. / Chang, C.Y. / Hsieh, S.H. / Yang, C.M. / Hsieh, H.P. / Wu, S.Y.
External links	J. Med. Chem. / PubMed:40391976
Methods	X-ray diffraction
Resolution	2.25 - 2.8 Å
Structure data	PDB-9kry: Crystal structure Of MerTK kinase domain in complex With compound 1 Method: X-RAY DIFFRACTION / Resolution: 2.25 Å PDB-9krz: Crystal structure Of MerTK kinase domain in complex with compound 11 Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-9ks9: Crystal structure of MerTK kinase domain in complex with compound 6 Method: X-RAY DIFFRACTION / Resolution: 2.8 Å
Chemicals	PDB-1l6j: Crystal structure of human matrix metalloproteinase MMP9 (gelatinase B). ChemComp-HOH: WATER PDB Unreleased entry PDB-1l6k: Unknown entry PDB Unreleased entry PDB-1l6l: Unknown entry
Source	homo sapiens (human)
Keywords	TRANSFERASE / kinase / dynamic dimer / Complex / TAM / Immune regulation / allosteric binding inhibitor / Type 2 inhibitor