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| Title | Conjugation to a transferrin receptor 1-binding Bicycle peptide enhances ASO and siRNA potency in skeletal and cardiac muscles. |
|---|---|
| Journal, issue, pages | Nucleic Acids Res., Vol. 53, Year 2025 |
| Publish date | Aug 15, 2024 (structure data deposition date) |
Authors | Ostergaard, M.E. / Carrer, M. / Anderson, B.A. / Afetian, M. / Bakooshli, M.A. / Santos, J.A. / Klein, S.K. / Capitanio, J. / Freestone, G.C. / Tanowitz, M. ...Ostergaard, M.E. / Carrer, M. / Anderson, B.A. / Afetian, M. / Bakooshli, M.A. / Santos, J.A. / Klein, S.K. / Capitanio, J. / Freestone, G.C. / Tanowitz, M. / Galindo-Murillo, R. / Gaus, H.J. / Dwyer, C.A. / Jackson, M. / Jafar-Nejad, P. / Rigo, F. / Seth, P.P. / Gaynor, K.U. / Stanway, S.J. / Urbonas, L. / St Denis, M.A. / Pellegrino, S. / Bezerra, G.A. / Rigby, M. / Gowans, E. / Van Rietschoten, K. / Beswick, P. / Chen, L. / Skynner, M.J. / Swayze, E.E. |
External links | Nucleic Acids Res. / PubMed:40207629 |
| Methods | X-ray diffraction |
| Resolution | 2.079 Å |
| Structure data | ![]() PDB-9gh7: |
| Chemicals | ![]() ChemComp-CA: ![]() ChemComp-GOL: ![]() PDB-1ile: ![]() ChemComp-HOH: |
| Source |
|
Keywords | TRANSPORT PROTEIN / Transferrin receptor protein 1 |
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homo sapiens (human)
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