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TitleState-dependent motion of a genetically encoded fluorescent biosensor.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 122, Page e2426324122-e2426324122, Year 2025
Publish dateNov 13, 2024 (structure data deposition date)
AuthorsRosen, P.C. / Horwitz, S.M. / Brooks, D.J. / Kim, E. / Ambarian, J.A. / Waidmann, L. / Davis, K.M. / Yellen, G.
External linksProc. Natl. Acad. Sci. USA / PubMed:40048274
MethodsX-ray diffraction
Resolution2.42 - 2.78 Å
Structure data

PDB-9ebw:
Chimeric fluorescence biosensor formed from a lactate-binding protein and GFP, bound to lactate
Method: X-RAY DIFFRACTION / Resolution: 2.78 Å

PDB-9ebx:
Chimeric fluorescence biosensor formed from a lactate-binding protein and GFP
Method: X-RAY DIFFRACTION / Resolution: 2.42 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-LAC:
LACTIC ACID

ChemComp-HOH:
WATER

Source
  • aequorea victoria (jellyfish)
  • helicobacter pylori (bacteria)
KeywordsFLUORESCENT PROTEIN / Biosensor / Binding protein / Chimera

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