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Structure paper

TitleStructural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system.
Journal, issue, pagesNucleic Acids Res., Vol. 53, Year 2025
Publish dateApr 22, 2024 (structure data deposition date)
AuthorsHu, R. / Guo, C. / Liu, X. / Lin, Y. / Yang, Z. / Li, Z. / Yang, Y. / Ma, E. / Li, Y. / Chen, J. / Liu, L.
External linksNucleic Acids Res. / PubMed:39997222
MethodsX-ray diffraction
Resolution3.18 - 6.7 Å
Structure data

PDB-8z8y:
Crystal structure of CrtAgo/CrtTIR-APAZ complex
Method: X-RAY DIFFRACTION / Resolution: 3.18 Å

PDB-8z92:
Crystal structure of CrtAgo/TIR-APAZ in complex with guide DNA and 16-nt target DNA
Method: X-RAY DIFFRACTION / Resolution: 3.85 Å

PDB-8z96:
Crystal structure of CrtAgo/TIR-APAZ in complex with guide DNA and 21-nt target DNA
Method: X-RAY DIFFRACTION / Resolution: 3.36 Å

PDB-9l9w:
Structure of SPARTA in complex with guide DNA and a 19nt target DNA
Method: X-RAY DIFFRACTION / Resolution: 5.87 Å

PDB-9l9x:
Structure of SPARTA in complex with guide DNA and a 20nt target DNA
Method: X-RAY DIFFRACTION / Resolution: 6.7 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • thermoflavifilum thermophilum (bacteria)
KeywordsDNA BINDING PROTEIN / NADase / DNA / Complex / DNA BINDING PROTEIN/DNA / DNA BINDING PROTEIN-DNA complex / Ago / TIR-APAZ

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