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TitleStructures of two lyssavirus glycoproteins trapped in pre- and post-fusion states and the implications on the spatial-temporal conformational transition along with pH-decrease.
Journal, issue, pagesPlos Pathog., Vol. 21, Page e1012923-e1012923, Year 2025
Publish dateMay 11, 2024 (structure data deposition date)
AuthorsYang, F. / Lin, S. / Yuan, X. / Shu, S. / Yu, Y. / Yang, J. / Ye, F. / Chen, Z. / He, B. / Li, J. ...Yang, F. / Lin, S. / Yuan, X. / Shu, S. / Yu, Y. / Yang, J. / Ye, F. / Chen, Z. / He, B. / Li, J. / Zhao, Q. / Ye, H. / Cao, Y. / Lu, G.
External linksPlos Pathog. / PubMed:39970183
MethodsX-ray diffraction
Resolution2.88 - 3.199 Å
Structure data

PDB-8zhw:
Structure of Mokola lyssavirus glycoprotein in post-fusion state
Method: X-RAY DIFFRACTION / Resolution: 3.199 Å

PDB-8zhz:
Structure of Ikoma lyssavirus glycoprotein in pre-fusion state
Method: X-RAY DIFFRACTION / Resolution: 2.88 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • lyssavirus mokola
  • ikoma lyssavirus
KeywordsVIRAL PROTEIN / Glycoprotein / lyssavirus / membrane fusion / VIRUS / Ikoma lyssavirus

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