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TitleStructural characterization of the ACDC domain from ApiAP2 proteins, a potential molecular target against apicomplexan parasites.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 81, Page 38-48, Year 2025
Publish dateFeb 5, 2024 (structure data deposition date)
AuthorsLe Berre, M. / Tubiana, T. / Reutersward Waldner, P. / Lazar, N. / Li de la Sierra-Gallay, I. / Santos, J.M. / Llinas, M. / Nessler, S.
External linksActa Crystallogr D Struct Biol / PubMed:39820027
MethodsX-ray diffraction
Resolution1.75 - 3.15 Å
Structure data

PDB-8rwu:
ACDC domain of the AP2-I transcription factor from Plasmodium vivax
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-8rxa:
ACDC domain of AP2-O5 from Plasmodium falciparum
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-8rxo:
ACDC domain of Plasmodium falciparum AP2-I transcription factor
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • plasmodium vivax (malaria parasite P. vivax)
  • plasmodium falciparum 3d7 (eukaryote)
KeywordsUNKNOWN FUNCTION / AP2-coincident domain mainly at the C-terminus / orthogonal four helix bundle / TRANSCRIPTION

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