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Structure paper

TitleCalcium Indicators with Fluorescence Lifetime-Based Signal Readout: A Structure-Function Study.
Journal, issue, pagesInt J Mol Sci, Vol. 25, Year 2024
Publish dateOct 24, 2024 (structure data deposition date)
AuthorsSimonyan, T.R. / Varfolomeeva, L.A. / Mamontova, A.V. / Kotlobay, A.A. / Gorokhovatsky, A.Y. / Bogdanov, A.M. / Boyko, K.M.
External linksInt J Mol Sci / PubMed:39684209
MethodsX-ray diffraction
Resolution2.05 - 2.65 Å
Structure data

PDB-9k8w:
Crystal structure of the calcium indicator GCaMP6s-BrUS in calcium-bound state
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-9k8x:
Crystal structure of the calcium indicator GCaMP6s-BrUS-145 in calcium-bounded state
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NA:
Unknown entry

Source
  • synthetic construct (others)
  • homo sapiens (human)
KeywordsFLUORESCENT PROTEIN / Genetically encoded calcium indicator / Calcium-bound state / Calcium-sensitive fluorescence lifetime / calcium saturated / Calcium bounded state

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